LP212213-5
Microsatellite instability marker NR24
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Description
Microsatellite instability (MSI) is a change in the number of repeats of a specific DNA marker in cancer cells compared to the number of repeats present in non-cancerous cells of the same patient. Different tumor types are associated with different MSI markers, and both the presence of MSI in specific markers as well as the the number of distinct markers demonstrating MSI is important. Tumor cells are classified as being stable, having high instability (MSI-H), or having low instability (MSI-L) based on the number of markers demonstrating MSI. MSI analysis may help guide therapy and be a prognostic indicator. Specific MSI markers include BAT25, BAT26, D2S123, D5S346, D17S2720, NR21, NR24 and MONO27. MSI has been most studied in colorectal cancer, and colorectal tumors that are MSI-H are more likely to be carcinomas than adenomas. MSI has also been studied in other types of cancer, including gastric cancer, breast cancer, lung cancer and Wilms tumor. Source: Regenstrief LOINC
Basic Part Properties
- Part Display Name
- Microsatellite instability marker NR24
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2016-04-29
- Construct for LOINC Short Name
- MSI mark NR24
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=LP212213-5
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
zh-CN | Chinese (China) | 微卫星不稳定性标记 NR24 Synonyms: 微卫星不稳定性(MSI)标记(标记物、 |
es-ES | Spanish (Spain) | Marcador NR24 de inestabilidad de microsatélites |
it-IT | Italian (Italy) | Marcatore NR24 di instabilità dei microsatelliti |
LOINC Copyright
Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright