LP220303-4
Hepatitis C virus genotype 1 NS5b gene
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Description
Nonstructural protein 5B (NS5b) is a viral protein found in hepatitis C virus (HCV), and has the main function of replicating the HCV viral RNA by using the viral positive RNA strand as its template and catalyzing the polymerization of ribonucleoside triphosphates (rNTP). PMID: 22303022 The S282T mutation has been identified as the common variant that can confer resistance to sofosbuvir, however, this mutation is not generally present in untreated patients with HCV. PMID: 24883006 Source: Regenstrief LOINC
Basic Part Properties
- Part Display Name
- Hepatitis C virus genotype 1 NS5b gene
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2016-06-28
- Construct for LOINC Short Name
- HCV Genotyp 1 NS5b
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=LP220303-4
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 丙型肝炎病毒基因型 1 NS5b 基因 Synonyms: 丙型肝炎病毒（C 型肝炎病毒、 |
| es-ES | Spanish (Spain) | Gen NS5b del genotipo 1 del virus de la Hepatitis C |
| it-IT | Italian (Italy) | Epatite C virus, genotipo 1 gene NS5b Synonyms: Gene NS5b genotipo 1 virus dell''epatite C |
| nl-NL | Dutch (Netherlands) | Hepatitis C-virus genotype 1 NS5b gen |
| pl-PL | Polish (Poland) | Gen NS5b HCV, genotyp 1 |
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