Version 2.78

Description

Dipeptidyl aminopeptidase-like protein 6 (DPPX) is a regulatory subunit of neuronal Kv4.2 potassium channel and is encoded by the DPPX gene. PMID: 25320100 DPPX is a type II membrane protein that binds to specific voltage-gated potassium channels and changes their biophysical characteristics. Alterations in the DPPX gene are associated with amyotrophic lateral sclerosis with idiopathic ventricular fibrillation. [NCBI Gene ID: 1804] IgG to DPPX is a biomarker for a frequently multifocal neurological disorder that develops insidiously, can be severe, responds to immunotherapy and is likely to relapse. Clinical symptoms associated with postive DPPX IgG include encephalopathy (with cortical, cerebellar or brainstem manifestations), myelopathy and autonomic dysfunction. PMID: 25320100 Source: Regenstrief LOINC

Basic Part Properties

Part Display Name
Dipeptidyl aminopeptidase-like protein 6
Part Type
Component (Describes the core component or analyte measured)
Created On
2016-09-29
Construct for LOINC Short Name
DPPX

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP230267-9

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 二肽氨基肽酶样蛋白 6
Synonyms: 二肽氨肽酶样蛋白 6;DPP6;DPPX;DPP VI;VF2;MRD33;DPL1;二肽氨基肽酶相关蛋白;二肽氨基肽酶 6;二肽氨基肽酶 IV-样蛋白;二肽氨基肽酶 VI;Dipeptidyl aminopeptidase-related protein;Dipeptidyl peptidase 6;Dipeptidyl peptidase IV-like protein;Dipeptidyl peptidase VI
es-ES Spanish (Spain) Proteina 6 tipo Dipeptidil aminopeptidasa
it-IT Italian (Italy) Dipeptidil aminopeptidasi-like proteina 6
nl-NL Dutch (Netherlands) dipeptidyl-aminopeptidase-achtig proteïne 6
Synonyms: dipeptidyl-aminopeptidase-like