LP230511-0
MDA5 Ab.IgG
Active
Description
Melanoma differentiation-associated gene 5 (MDA5) senses intracellular pathogens. Through a complex cascade of intracellular interactions with a myriad of activators and regulators MDA5 contributes to the production of interferon-alpha and pro-inflammatory chemokines and cytokines. Antibodies to MDA5 have been linked to a subtype of dermatomyositis (DM) associated with low-grade to absent muscle inflammation, acute skin manifestations, hyperferritinemic status, frequent and rapidly progressive interstitial lung disease (ILD) and a poor prognosis.( https://clinicalmolecularallergy.biomedcentral.com/articles/10.1186/s12948-015-0031-y) Source: Regenstrief LOINC
Basic Part Properties
- Part Display Name
- MDA5 IgG
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2016-10-05
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=LP230511-0
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
pl-PL | Polish (Poland) | MDA5 Ab.IgG Synonyms: PrzeciwciaĆa IgG do MDA5 |
LOINC Copyright
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