LP248177-0
Neisseria meningitidis serogroup Y synF gene
Active
Descriptions
SynF is a capsule biosynthesis gene that uniquely identifies Neisseria meningitidis serogroup Y from the other meningococcal serogroups.[https://www.cdc.gov/meningitis/lab-manual/chpt10-pcr.html] There has been a large increase in the proportion of meningococcal disease caused by N. meningitidis serogroup Y since 1989. In the mid-1990s, the incidence increased substantially in the United States (US) and during the past 10 years, it has also increased in Canada, Columbia and Norway. A potential cause of this shift is the fact that the polysaccharide capsule based vaccine formulated for serogroups A, C, W-135 and Y is ineffective against children under 2 years of age and has only been useful for outbreaks of the disease. Recent vaccines for serogroups A and C have proven to be more effective in that age group which has led to serogroup Y being the most likely cause of pneumonia from Neisseria meningitidis. Diagnosis can be confirmed with positive blood, CSF or pleural fluid cultures. PMID: 26057210 Source: Regenstrief LOINC
Neisseria meningitidis is identified based on the species-specific targets sodC and ctrA. Individual Neisseria meningitidis serogroups are identified based on their serogroup-specific genes for capsule biosynthesis. Serogroups and the genes that identify them are as follows:
N. meningitidis serogroup A: sacB
N. meningitidis serogroup B: synD
N. meningitidis serogroup C: synE
N. meningitidis serogroup w135: synG
N. meningitidis serogroup X: xcbB
N. meningitidis serogroup Y: synF
[https://www.cdc.gov/meningitis/lab-manual/chpt10-pcr.html]
Source: Regenstrief LOINC
Basic Part Properties
- Part Display Name
- Neisseria meningitidis serogroup Y synF gene
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2017-02-08
- Construct for LOINC Short Name
- N men sg Y synF
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- CodeSystem lookup
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Gen synF del serogrupo Y de Neisseria meningitidis |
| zh-CN | Chinese (China) | 脑膜炎奈瑟菌血清群 Y synF 基因 |
| it-IT | Italian (Italy) | Neisseria meningitidis sierogruppo Y, gene synF Synonyms: Gene synF di Neisseria meningitidis sierogruppo Y |
| nl-NL | Dutch (Netherlands) | Neisseria meningitidis serogroep Y synF-gen Synonyms: Neisseria meningitidis serogroep Y synF gen |
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