Version 2.77


Oxycodone is in the opioid drug class and is a potent pain reliever. Noroxymorphone is a major secondary metabolite of oxycodone. It is formed after O-demethylation of noroxycodone by CYP2D6 and to a lesser extent by N-demethylation of oxymorphone by Cyp3A4 and 2D6. Noroxymorphone has minimal analgesic effect when oxycodone is administered orally or systemically. Noroxymorphone is a powerful agonist to the mu-opioid receptor when oxycodone is administered intrathecally suggesting that noroxymorphone does not readily cross the blood-brain barrier. ( PMID: 18227301) ( Source: Regenstrief LOINC

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Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Noroximorfona
zh-CN Chinese (China) 去甲基羟吗啡酮
Synonyms: 脱甲基羟吗啡酮;脱甲基氧吗啡酮;去甲基氧吗啡酮
it-IT Italian (Italy) Norossimorfone
nl-NL Dutch (Netherlands) noroxymorfon