Version 2.77

Description

Oxycodone is in the opioid drug class and is a potent pain reliever. Noroxymorphone is a major secondary metabolite of oxycodone. It is formed after O-demethylation of noroxycodone by CYP2D6 and to a lesser extent by N-demethylation of oxymorphone by Cyp3A4 and 2D6. Noroxymorphone has minimal analgesic effect when oxycodone is administered orally or systemically. Noroxymorphone is a powerful agonist to the mu-opioid receptor when oxycodone is administered intrathecally suggesting that noroxymorphone does not readily cross the blood-brain barrier. ( PMID: 18227301) (http://www-3.unipv.it/balto98/Lezioni%20IUSS/noroxymorphone.pdf) Source: Regenstrief LOINC

Basic Part Properties

Part Display Name
Noroxymorphone
Part Type
Component (Describes the core component or analyte measured)
Created On
2017-03-16
Construct for LOINC Short Name
Noroxymorphone

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP248581-3

Language Variants Get Info

Tag Language Translation
es-ES Spanish (Spain) Noroximorfona
zh-CN Chinese (China) 去甲基羟吗啡酮
Synonyms: 脱甲基羟吗啡酮;脱甲基氧吗啡酮;去甲基氧吗啡酮
it-IT Italian (Italy) Norossimorfone
nl-NL Dutch (Netherlands) noroxymorfon