LP248581-3
Noroxymorphone
Active
Description
Oxycodone is in the opioid drug class and is a potent pain reliever. Noroxymorphone is a major secondary metabolite of oxycodone. It is formed after O-demethylation of noroxycodone by CYP2D6 and to a lesser extent by N-demethylation of oxymorphone by Cyp3A4 and 2D6. Noroxymorphone has minimal analgesic effect when oxycodone is administered orally or systemically. Noroxymorphone is a powerful agonist to the mu-opioid receptor when oxycodone is administered intrathecally suggesting that noroxymorphone does not readily cross the blood-brain barrier. ( PMID: 18227301) (http://www-3.unipv.it/balto98/Lezioni%20IUSS/noroxymorphone.pdf) Source: Regenstrief LOINC
Basic Part Properties
- Part Display Name
- Noroxymorphone
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2017-03-16
- Construct for LOINC Short Name
- Noroxymorphone
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=LP248581-3
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
es-ES | Spanish (Spain) | Noroximorfona |
zh-CN | Chinese (China) | 去甲基羟吗啡酮 Synonyms: 脱甲基羟吗啡酮; |
it-IT | Italian (Italy) | Norossimorfone |
nl-NL | Dutch (Netherlands) | noroxymorfon |
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