LP249019-3

Bombay phenotype

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Description

Red blood cells (RBCs) have surface antigens that play a role in determining compatibility for blood transfusions and organ transplants. The common antigens on RBCs are from the ABO system and include A, B and H antigens. The H antigen is a carbohydrate on the RBC surface which is the biosynthetic precursor required for the expression of the A and B antigens. Cells that express H antigen and lack A and B antigens are, by default, in blood group O. In rare cases, the H antigen is not expressed on the red cell membrane at all, which is described as having an O sub h or Bombay phenotype. Individuals with the Bombay phenotype produce antibodies to the A, B and H antigens, which antibodies are capable of activating complement and causing hemolysis. The only blood that a patient with Bombay phenotype may receive is that from another person who also expresses the Bombay phenotype. (AABB Technical Manual, 18th edition) Source: Regenstrief LOINC

Basic Part Properties

Part Name

Bombay phenotype

Part Display Name

Bombay phenotype

Part Type

Component (Describes the core component or analyte measured)

Created On

2017-04-03

Construct for LOINC Short Name

Bombay phenotype

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Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://loinc.org/license for the full LOINC copyright and license.