LP264211-6
H little y
Active
Descriptions
The first example of anti-Doa, reactive with 64% of the Caucasian population, was reported by Swanson et al. in 1965. It was not until 1972 that Molthan et al. reported the antithetical antibody anti-Dob. Thus, the Dombrock blood group system was defined and was estimated to be the fifth most useful blood group marker in Caucasians. However, limited examples of both antibodies greatly restricted broad investigations. The Dombrock system remained a simple two allele system until 1992, when Banks et al. reported that the red cells of the rare Gy(a-) Hy(a-) Jo(a-) individuals were also Do(a-b-). Consequently, these three high incidences blood factors were included within the system. Interestingly, it had already been known that all Gy(a-) red cells lacked both Hya and Joa antigens and that Hy(a-) red cells lacked Joa antigens. Ironically, Swanson reported the first examples of both anti-Doa (in 1965) and anti-Gya (1967) but as anti-Dob was, at that time, yet to be discovered any association with Doa and Gya could not be deduced. Source: Serum, Cells and Rare Fluid Exchange, Dombrock group
The Hy antigen is one of eight members of the Dombrock blood group system. The Hy antigen is only commonly expressed in people with African ancestry and never seen in caucasians. Because the supply for antisera to Dombrock antigens is very limited and have weak reactions with Dombrock antigens, compatibility testing is best done by single nucleotide polymorphism methods. The two antibodies anti-Doa and anti-Dob have caused acute and delayed hemolytic transfusion reactions. There is little clinical information about the other Dombrock antibodies other than that none have caused hemolytic disease of the newborn. [AABB Technical Manual, 18th edition, pp354-355] Source: Regenstrief LOINC
Basic Part Properties
- Part Display Name
- Hy
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2017-10-24
- Construct for LOINC Short Name
- Hy
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=LP264211-6
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | Hy |
| it-IT | Italian (Italy) | H y minuscola |
| zh-CN | Chinese (China) | Hy Synonyms: H little y |
| nl-NL | Dutch (Netherlands) | H kleine y Synonyms: Hy |
LOINC Copyright
Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright