LP265685-0
ALK gene
Active
Description
The ALK (ALK receptor tyrosine kinase) gene [HGNC Gene ID:427] is located on chromosome 2 at 2p23.2-p23.1. This gene encodes a receptor tyrosine kinase, which belongs to the insulin receptor superfamily, and has been found to be rearranged, mutated, or amplified in a series of tumors including anaplastic large cell lymphomas, neuroblastoma, and non-small cell lung cancer. The chromosomal rearrangements are the most common genetic alterations in this gene, which result in creation of multiple fusion genes in tumorigenesis, including ALK (chromosome 2)/EML4 (chromosome 2), ALK/RANBP2 (chromosome 2), ALK/ATIC (chromosome 2), ALK/TFG (chromosome 3), ALK/NPM1 (chromosome 5), ALK/SQSTM1 (chromosome 5), ALK/KIF5B (chromosome 10), ALK/CLTC (chromosome 17), ALK/TPM4 (chromosome 19), and ALK/MSN (chromosome X).[provided by RefSeq, Jan 2011] [NCBI Gene ID:238] Source: National Center for Biotechnology Information (NCBI) Gene
Basic Part Properties
- Part Display Name
- ALK gene
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2018-01-05
- Construct for LOINC Short Name
- ALK gene
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=LP265685-0
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| it-IT | Italian (Italy) | ALK, gene Synonyms: Gene ALK |
| es-ES | Spanish (Spain) | Gen ALK |
| zh-CN | Chinese (China) | ALK 基因 |
| nl-NL | Dutch (Netherlands) | ALK-gen |
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