Version 2.78

Description

The NY-ESO-1 antigen (also referred to as CTAG1) was originally identified in esophageal cancer cells in New York City. It is only found in the developing sperm and is lost as the sperm differentiates. NY-ESO-1 is a member of the cancer-testis gene family which only express antigens in germ cells. NY-ESO-1 is not expressed in normal somatic cell tissue, but is often expressed in cancer cells. Its function is not known due in part because it lacks evolutionary homologs, eliminating the ability to use animal models for research. Because it is rarely present in normal tissue cells, but often present in cancer cells it is a useful biomarker for the detection of early cancer. NY-ESO-1 has been found in one third to one fourth of all melanoma, lung, esophageal, liver, gastric, prostate, ovarian, or bladder cancers. In cancers including colorectal, pancreatic, renal, and lymphomas, NY-ESO-1 is very rarely identified. PMID: 16860654 Ongoing studies are investigating the utility of the NY-ESO-1 antibody being used as a biomarker for the early detection of lung and liver cancer in high risk asymptomatic patients. PMID: 21733826 PMID: 25093332 Source: Regenstrief LOINC

Basic Part Properties

Part Display Name
NY-ESO-1 Ab
Part Type
Component (Describes the core component or analyte measured)
Created On
2018-03-13
Construct for LOINC Short Name
NY-ESO-1 Ab

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP266570-3

Language Variants Get Info

Tag Language Translation
pl-PL Polish (Poland) NY-ESO-1 Ab
Synonyms: Przeciwciała do NY-ESO-1