LP266572-9
SOX-2 Ab
Active
Description
SOX-2 is a transcription factor essential in the early development and maintenance of pluripotent embryonic stem cells and stem cells in a number of adult tissues of mammals. SOX-2 is important to continued self-renewal and to maintain the required numbers of basal cells in adult tracheal epithelium. It directs the developing branches of the bronchial tree and the growth of the epithelium of the airways. SOX-2 has been found to be overexpressed in squamous cell lung cancer when compared to adenocarcinomas. PMID: 20548776 Ongoing studies are investigating the utility of the SOX-2 antibody being used as a biomarker for the early detection of lung cancer in high risk asymptomatic patients. PMID: 21733826 Source: Regenstrief LOINC
Basic Part Properties
- Part Display Name
- SOX-2 Ab
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2018-03-13
- Construct for LOINC Short Name
- SOX-2 Ab
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=LP266572-9
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| pl-PL | Polish (Poland) | SOX-2 Ab Synonyms: Przeciwciała do SOX-2 |
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