LP266717-0
Fluoroquinolone
Active
Description
Fluorquinolones are among most beneficial drugs used to treat multi-drug resistant Mycobacterium tuberculosis (MDR-TB) infections. The fluorquinolones affect the activity of DNA gyrase by reducing the cell's ability for DNA replication and transcription. DNA gyrase in Mycobacterium tuberculosis (TB) is made of two subunits that are encoded by gyrA and gyrB. Mutations in the gyrA quinolone resistance-determining region (QRDR) are responsible for causing most of the drug resistance of TB to the fluoroquinolones. The gyrB mutations have a much smaller impact on TB resistance to the fluoroquinolones. PMID: 26763957 Source: Regenstrief LOINC
Basic Part Properties
- Part Display Name
- Fluoroquinolone
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2018-03-27
- Construct for LOINC Short Name
- FLQ
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=LP266717-0
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| it-IT | Italian (Italy) | Fluorochinolone |
| zh-CN | Chinese (China) | 氟喹诺酮 Synonyms: 氟喹诺酮类抗生素; |
| es-ES | Spanish (Spain) | Fluoroquinolona |
| nl-NL | Dutch (Netherlands) | fluorchinolon |
LOINC Copyright
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