Version 2.77

Description

Bacterial resistance to macrolide drugs has increased in conjunction with their heavy use in both medicine and animal husbandry. While there are a number of mechanisms bacteria use to resist the efficacy of drug treatment, the one used by macrolides is to bind to the large 50S subunit of the bacterial ribosome and interfere with protein synthesis. Changes of specific nucleotides in the 23S rRNA inside the large ribosomal unit are the root cause of many instances of bacterial resistance to macrolides. PMID: 11120937 Source: Regenstrief LOINC

Basic Part Properties

Part Display Name
Bacterial 23S rRNA gene azithromycin resistance mutation
Part Type
Component (Describes the core component or analyte measured)
Created On
2018-03-29
Construct for LOINC Short Name
Bact 23S rRNA azith res mut

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP266750-1

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 细菌 23S rRNA 基因阿奇霉素耐药性突变
Synonyms: 细菌 23S rRNA 基因阿奇霉素耐药性(抗性、耐性、耐药、抗药、抗药性、耐受、耐药型)突变
es-ES Spanish (Spain) Mutación del Gen 23S rRNA de resistencia a azitromicina
it-IT Italian (Italy) Gene batterico 23S rRNA, mutazione resistenza a azitromicina
Synonyms: Mutazione di resistenza a azitromicina di gene batterico 23S rRNA
nl-NL Dutch (Netherlands) bacteriële azitromycineresistentie 23S-rRNA-genmutatie