LP267926-6
t(14;20)(q32;q12)(IGH,MAFB)
Active
Description
Translocations of the immunoglobulin heavy chain (IgH) gene at 14q32 are routinely present in patients with B lymphoid malignancies and is one of the most common mutations in patients with multiple myeloma (MM). The t(14;20)(q32;q12) translocation may cause the deregulation of existing oncogenes or produce new hybrid genes with altered characteristics. The t(14;20) translocation is detected in very early stages of disease, indicating it may play a role in instigating its development. IgH translocations increase as the disease progresses. The t(14q32) translocation is present in 74% of patients with MM and in 85% of patients with plasma cell leukemia. PMID: 15257707 Source: Regenstrief LOINC
Basic Part Properties
- Part Name
- t(14;20)(q32;q12)(IGH,MAFB)
- Part Display Name
- t(14;20)(q32;q12)(IGH,MAFB)
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2018-06-19
- Construct for LOINC Short Name
- t(14;20)(IGH,MAFB)
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=LP267926-6
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| es-ES | Spanish (Spain) | t(14; |
| it-IT | Italian (Italy) | t(14; |
| zh-CN | Chinese (China) | t(14; Synonyms: 易位(14; |
| fr-CA | French (Canada) | t(14; |
| el-GR | Greek (Greece) | t(14; Synonyms: t(14; |
LOINC Copyright
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