LP268299-7
Epithelial cell adhesion molecule Ab
Active
Description
EpCAM, also known as epithelial cell adhesion molecule, is the target of one of the several autoantibodies tested to detect liver cancer in its early stages. EpCAM is a cell surface molecule with a number of different functions including cell adhesion, intracellular signaling, migration, proliferation and differentiation. It is normally expressed in many human tissues, but is overexpressed in some neoplasms, including liver, breast, ovarian and gallbladder cancers. EpCAM facilitates the growth of tumors by switching on the proto-oncogene c-MYC. A poor survival rate is associated with the overexpression of EpCAM in liver cancers. Therapeutic antibodies to EpCAM are often used to treat epithelial tumors. PMID: 23482411 Source: Regenstrief LOINC
Basic Part Properties
- Part Display Name
- EpCAM Ab
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2018-08-08
- Construct for LOINC Short Name
- EpCAM Ab
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=LP268299-7
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| pl-PL | Polish (Poland) | Molekuła adhezyjna komórek nabłonkowych Ab Synonyms: Przeciwciała do antygenu adhezyjnego komórek nabłonkowych |
LOINC Copyright
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