Version 2.78

Description

MET gene amplification studies evaluate the number of copies of the MET gene present in a single cell. Amplification is determined based on the MET gene copy number and MET to centromere ratio. Different criteria have been proposed for what constitutes amplification, including a MET to centromere ratio of >= 2, an average MET gene copy number >=5, and at least 15 gene copies in 10% of the tumor cell nuclei that were counted. MET amplification is associated with worse prognosis in a variety of cancers, including non-small cell lung and gastroesophageal cancer. PMID: 27926778 Source: Regenstrief LOINC

Basic Part Properties

Part Display Name
MET gene amplification
Part Type
Component (Describes the core component or analyte measured)
Created On
2018-10-26
Construct for LOINC Short Name
MET amp

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP269809-2

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) MET 基因扩增
Synonyms: MET 原癌基因;受体酪氨酸激酶 Met;肝细胞生长因子受体;hepatocyte growth factor receptor;MET;MET proto-oncogene;receptor tyrosine kinase Met;AUTS9;HGFR;RCCP2;c-Met;DFNB97;OSFD
es-ES Spanish (Spain) Amplificación del gen MET
it-IT Italian (Italy) Gene MET, amplificazione
Synonyms: Amplificazione gene MET
nl-NL Dutch (Netherlands) MET-genamplificatie