LP269813-4
Thiopurine methyltransferase activity panel
Active
Description
Thiopurine methyltransferase (TPMT) is an enzyme that catalyzes the S-methylation of thiopurine drugs including 6-mercatptopurine, thioguanine, and azathioprine (AZA). These drugs are used to treat acute lymphoblastic leukemia, inflammatory bowel disease, rheumatoid arthritis, and organ transplant rejection. Patients with low or absent TPMT activity are at increased risk for toxicity due to increased accumulation of unmetabolised drug. Information from Current Clinical Pharmacology. 2006;1:119-128. Source: Regenstrief Institute
Basic Part Properties
- Part Display Name
- Thiopurine methyltransferase activity panel
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2018-10-26
- Construct for LOINC Short Name
- TPMT activity panel
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=LP269813-4
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 硫嘌呤甲基转移酶活性组套 Synonyms: 硫嘌呤甲基转移酶（TPMT、 |
| es-ES | Spanish (Spain) | Panel de la actividad de la tiopurina metil transferasa |
| it-IT | Italian (Italy) | Tiopurina metiltransferasi, panel attività Synonyms: Panel attività tiopurina metiltransferasi |
LOINC Copyright
Copyright © 2024 Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright