LP28549-1
Adefovir
Active
Description
Adefovir dipivoxil, previously called bis-POM PMEA, works by blocking reverse transcriptase, an enzyme that is crucial for the hepatitis B virus (HBV) to reproduce in the body. Adefovir was initially developed for treatment of HIV, sold under the brand name Preveon. It was discontinued in 1999 for HIV but later approved in 2002 by the FDA for treatment of hepatitis B (HBV) and sold under the brand name Hepsera.(http://en.wikipedia.org/wiki/Adefovir)
There is some evidence that adefovir levels correlate with viral clearance, but viral resistance can occur. (http://www.ncbi.nlm.nih.gov/pmc/articles/PMC2916322/). Adefovir is associated with renal toxicity.
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Source: Wikipedia, Adefovir
Basic Part Properties
- Part Display Name
- Adefovir
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2001-09-07
- Construct for LOINC Short Name
- Adefovir
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=LP28549-1 - ConceptMap translate
- https:
//fhir.loinc.org/ConceptMap/$translate?system=http: //loinc.org&code=LP28549-1
Language Variants Get Info
Tag | Language | Translation |
---|---|---|
zh-CN | Chinese (China) | 阿德福韦 Synonyms: 9-[2-[双(特戊酰氧基甲氧基)磷酰甲氧基]乙基]腺嘌呤; |
fr-CA | French (Canada) | Adéfovir |
et-EE | Estonian (Estonia) | Adefoviir |
es-ES | Spanish (Spain) | Adefovir |
it-IT | Italian (Italy) | Adefovir |
tr-TR | Turkish (Turkey) | Adefovir |
ru-RU | Russian (Russian Federation) | Адефовир |
nl-NL | Dutch (Netherlands) | adefovir |
fr-BE | French (Belgium) | Adéfovir |
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