LP28587-1
Pyridoxal phosphate
Active
Descriptions
This is the active form of VITAMIN B 6 serving as a coenzyme for synthesis of amino acids, neurotransmitters (serotonin, norepinephrine), sphingolipids, aminolevulinic acid. During transamination of amino acids, pyridoxal phosphate is transiently converted into pyridoxamine phosphate (PYRIDOXAMINE). Source: National Library of Medicine, MeSH 2006
When mapping be careful to distinguish the word pyridoxal (A is the 2nd to last letter) from pyridoxol (letter O is the 2nd to last letter). These are both forms or preforms of vitamin B6. Pyridoxine - the usual name for B6 is also called pyridoxol. These both get converted to Pyridoxine 5-Phosphate the biologically active form (also called Pyridoxol 5-phosphate)
There are three natural forms of vitamin B6, pyridoxine (also called "pyridoxol") pyridoxamine and pyridoxal. All of these forms are converted into a single biologically active form, pyridoxal 5-phosphate. All three forms of vitamin B6 are heterocyclic organic compounds. Green plants are a natural source of pyridoxal, and its deficiency in humans can lead to serious complications such as epilepsy and seizures.
Source: Regenstrief Help
Pyridoxal phosphate is a derivative of Vitamin B6 and is used by enzymes in all organisms. The majority of enzymes which depend on pyridoxal phosphate are associated with pathways involving amino acids, such as amino group transfer, decarboxylation and other important biochemical processes. [PMCID:1326353]
When measuring AST and/or ALT without pyridoxal-5-phosphate (P-5-P), the rate of the decrease of NADH is directly proportional to the AST/ALT (respectively)-activity in the specimen. Testing for AST and/or ALT with the addition of P-5-P stabilizes the transaminases in the specimen and avoids falsely low values in specimens of patients suffering from either myocardial infarction or liver disease, who have an insufficient amount of P-5-P in their blood.
Source: Regenstrief LOINC
Basic Part Properties
- Part Display Name
- Pyridoxal phosphate
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2001-10-15
- Construct for LOINC Short Name
- Pyridoxal Phos
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 磷酸吡哆醛 Synonyms: PLP; |
| fr-CA | French (Canada) | Pyridoxal phosphate |
| et-EE | Estonian (Estonia) | Püridoksaalfosfaat |
| es-ES | Spanish (Spain) | Piridoxal fosfato |
| it-IT | Italian (Italy) | Piridossal fosfato |
| tr-TR | Turkish (Turkey) | Piridoksal fosfat |
| ru-RU | Russian (Russian Federation) | Пиридоксаль фосфат Synonyms: Пиридоксальфосфат |
| nl-NL | Dutch (Netherlands) | pyridoxalfosfaat |
| fr-BE | French (Belgium) | Pyridoxal phosphate |
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