Version 2.77

Description

Factor VIII replacement is the foundational treatment for hemophilia A, and the developement of alloantibodies (known as inhibitors) against the replacement factor is the most important complication causing morbidity in hemophilia patients. Antibodies against factor VIII can be inhibitory or noninhibitory, with inhibitors generally being polycloncal IgG directed against the A2, A3 and C2 domains of the factor VIII molecule. The resulting steric hindrance can block functional epitopes including FIX, phospholipid, or von Willebrand binding sites PMID: 23610614. Source: Regenstrief LOINC

Basic Part Properties

Part Display Name
Coagulation factor VIII inhibitor
Part Type
Component (Describes the core component or analyte measured)
Created On
2002-06-18
Construct for LOINC Short Name
Fact VIII Inhib

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP29023-6

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 凝血因子 VIII 抑制剂
Synonyms: 凝血因子 VIII（凝血因子Ⅷ、因子 VIII、因子Ⅷ）抑制剂
fr-CA French (Canada) Inhibiteur du facteur VIII
et-EE Estonian (Estonia) VIII faktori inhibiitor
es-ES Spanish (Spain) Factor de coagulación VIII inhibido
it-IT Italian (Italy) Fattore di coagulazione VIII, inibitore
Synonyms: Inibitore del fattore di coagulazione VIII
tr-TR Turkish (Turkey) Koagülasyon faktörü VIII inhibitörü
ru-RU Russian (Russian Federation) Коагуляции фактор VIII ингибитор
nl-NL Dutch (Netherlands) stollingsfactor VIII remmer
fr-BE French (Belgium) Inhibiteur du facteur VIII
pl-PL Polish (Poland) Inhibitor Czynnika krzepnięcia VIII