LP29040-0
Complement total hemolytic CH50
Active
Description
Complement total hemolytic CH50 testing is used to monitor Systemic Lupus Erythematosus (SLE) patients' response to therapy. It is also used to evaluate complement component deficiency, complement activity in patients with immune complexes , glomerulonephritis, rheumatoid arthritis, and cryoglobulinemia. Complement is a system of 25 proteins associated with cell membranes and present in plasma; it plays a vital role in the function of the immune system. Complement components function in the "classical" and "alternative" pathways. The CH50 assay mainly evaluates the classical pathway. Complement proteins are activated during the acute phase of inflammation or infection. Decreased levels of complement components occur during hypercatabolism, expenditure in immune complexes or due to hereditary deficiency. Decreasing complement levels may signal upcoming clinical problems, especially lupus nephritis. Source: Regenstrief Institute
Basic Part Properties
- Part Display Name
- Complement total hemolytic CH50
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2002-06-18
- Construct for LOINC Short Name
- CH50
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- CodeSystem lookup
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 补体总溶血活性 Ch50 |
| fr-CA | French (Canada) | Complément hémolytique total CH50 |
| et-EE | Estonian (Estonia) | Komplemendi klassikalise tee aktiivsus CH50 seerumis |
| es-ES | Spanish (Spain) | Complemento hemolitico total CH50 |
| it-IT | Italian (Italy) | Complemento emolitico totale CH50 |
| el-GR | Greek (Greece) | Ολικό αιμολυτικό συμπλήρωμα CH50 |
| tr-TR | Turkish (Turkey) | Kompleman total hemolitik CH50 |
| ru-RU | Russian (Russian Federation) | Комплемент общий гемолитический CH50 |
| nl-NL | Dutch (Netherlands) | complement totaal hemolytisch CH50 |
| fr-BE | French (Belgium) | Hémolyse CH50 |
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