LP29071-5
Immunoglobulin light chains.free
Active
Description
Healthy patients have the majority of light chains in serum bound to heavy chains. Low levels of free light chains (unbound) are normal due to the over-production and secretion of free light chains by plasma cells. In the kidneys, the free light chains are selectively reabsorbed by the tubular cells, so their presence in urine is likely due to secretion into the urinary tract. Elevation of monoclonal free light chains in serum or urine signal malignant plasma cell proliferation (multiple myeloma), primary amyloidosis, or light chain deposition disease. Elevation of polyclonal free light chains suggests autoimmune diseases such as systemic lupus erythematosus. (Information from Freelite Beckman Coulter IMMAGE II package insert, Version 23, Feb 2009) Source: Regenstrief Institute
Basic Part Properties
- Part Display Name
- Immunoglobulin light chains.free
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2002-06-18
- Construct for LOINC Short Name
- BJ Protein Free
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- CodeSystem lookup
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Language Variants Get Info
Tag | Language | Translation |
---|---|---|
zh-CN | Chinese (China) | 免疫球蛋白轻链.游离型 Synonyms: 免疫球蛋白轻链.游离; |
fr-CA | French (Canada) | Chaînes légères des immunoglobulines.libres |
et-EE | Estonian (Estonia) | Immuunglobuliini vabad kerged ahelad |
es-ES | Spanish (Spain) | Cadenas ligeras libres de inmunoglubulina |
it-IT | Italian (Italy) | Immunoglobuline, catene leggere.libere Synonyms: Catene leggere libere delle immunoglobuline |
tr-TR | Turkish (Turkey) | Immunoglobulin hafif zincirler.serb |
ru-RU | Russian (Russian Federation) | Иммуноглобулин лёгкие цепи.свободный |
nl-NL | Dutch (Netherlands) | immunoglobuline lichte ketens.vrij |
fr-BE | French (Belgium) | Chaînes légères des immunoglobulines.libres Synonyms: LC. Libres, FLC |
pl-PL | Polish (Poland) | Łańcuchy lekkie immunoglobulin.wolne Synonyms: Wolne lekkie łańcuchy immunoglobulin |
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