Version 2.77


A monoclonal band (M-spike, monoclonal protein isotype) is often found in patients with monoclonal gammopathies. Following protein electrophoresis, immunofixation is used to identify the immunoglobulin heavy chain and/or light chain. Monoclonal peaks greater than 3 g/dL and IgG or IgA are seen in patients with Multiple Myeloma (MM). A monoclonal peak greater than 3 g/dL and IgM is seen in patients with macroglobulinemia. An alternate methodology for identifying the monoclonal protein isotype is MALDI-TOF, in which known information regarding the unique mass of each isotype is used to determine and quantify the isotype present in the patient sample based on the mass spectra generated from the sample. Source: Regenstrief LOINC

Basic Part Properties

Part Display Name
Part Type
Component (Describes the core component or analyte measured)
Created On
Construct for LOINC Short Name
M Protein

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup$lookup?system=

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 蛋白质.单克隆型
Synonyms: M 区带;M 峰;M 带;M 蛋白;副蛋白;单克隆区带;单克隆型蛋白质;单克隆型蛋白质区带;单克隆峰;单克隆性蛋白质;单克隆性蛋白质区带;单克隆蛋白质区带;异常蛋白;病变蛋白;蛋白质.单克隆
fr-CA French (Canada) Protéines.monoclonales
et-EE Estonian (Estonia) Valk.monoklonaalne
es-ES Spanish (Spain) Proteinas monoclonales
it-IT Italian (Italy) Proteina.monoclonale
tr-TR Turkish (Turkey) Protein.monoklonal
ru-RU Russian (Russian Federation) Протеин.моноклональный
nl-NL Dutch (Netherlands) eiwit.monoclonale
fr-BE French (Belgium) Protéines.monoclonales
pl-PL Polish (Poland) Białko monoklonalne