LP31258-4
Clostridium botulinum toxin A
Active
Description
Botulinum toxin is a neurotoxin produced by Clostridium botulinum, an anaerobic, gram-positive, spore-forming rod found on plants, in soil, water and the intestinal tracts of animals. Eight exotoxins (A, B, C1, C2, D, E, F and G) have been identified, all of which interfere with neural transmission by blocking the release of acetylcholine, the principal neurotransmitter at the neuromuscular junction. The toxins are used in the clinical management of various spastic medical conditions, strabismus and focal dystonias, hemifacial spasms, headaches, hyper-salivation and hyperhidrosis. Type A is the most potent toxin. In 2002 it was approved by the U.S. Food and Drug Administration for cosmetological uses. It is administered by injection into muscles or glands with the effects lasting approximately three months. Most patients require multiple treatments over many years and some develop tolerance to the injections due to the development of neutralizing antibodies to the toxin. Side effects are minor and transient. PMID: 20418969 Source: Regenstrief LOINC
Basic Part Properties
- Part Display Name
- Clostridium botulinum toxin A
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2003-02-04
- Construct for LOINC Short Name
- C bot Tox A
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 肉毒梭菌毒素 A Synonyms: 肉毒 A; |
| fr-CA | French (Canada) | Toxine Clostridium botulinum A |
| et-EE | Estonian (Estonia) | Clostridium botulinum toksiin A |
| es-ES | Spanish (Spain) | Toxina A del Clostridium botulinum |
| it-IT | Italian (Italy) | Clostridium botulinum, tossina A Synonyms: Tossina A di Clostridium botulinum |
| tr-TR | Turkish (Turkey) | Clostridium botulinum toksin A |
| ru-RU | Russian (Russian Federation) | Clostridium botulinum токсин A |
| nl-NL | Dutch (Netherlands) | Clostridium botulinum toxine A |
| fr-BE | French (Belgium) | Toxine Clostridium botulinum A Synonyms: Clostridium botulinum A. Toxine |
| pl-PL | Polish (Poland) | Clostridium botulinum toksyna A Synonyms: Toksyna A Clostridium botulinum |
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