LP31592-6
Interleukin 1 alpha
Active
Descriptions
Interleukin-1 alpha (IL-1α) is a protein that in humans is encoded by the IL1A gene. The protein encoded by this gene is a cytokine of the interleukin-1 family. Interleukin-1 alpha possesses a wide spectrum of metabolic, physiological, haematopoietic activities, and plays one of the central roles in the regulation of the immune responses. It binds to the interleukin-1 receptor. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia
The Interleukins belong to the family termed cytokines. They are peptides used by immune and inflammatory cells to communicate and control cell operations. The cytokines have some similar actions to the Growth Factors but Growth Factors regulate proliferation of non-immune cells. Interleukin 1a is a 17,500 molecular weight peptide derived primarily from macrophages, fibroblasts, endothelial cells, and B cells. The major target cells are T and B cells, Fibroblasts, and Hepatocytes. Interleukin 1a shares a receptor with Interleukin 1b although they are significantly different structurally. Interleukin 1a promotes antigen specific immune responses, inflammation, Prostaglandin secretion, Colony Stimulating Factors, proteoglycanase, collagenase, and gelatinase activity, and release of Interleukin 2 from T cells. Levels are stimulated by liposaccharide, endotoxins, inflammatory agents, lectin, Tumor Necrosis Factor, and Interferons. Levels are suppressed by Corticosteroids, Prostaglandin E2, and suppressant lymphocytes Source: Inter Science Institute, Inter Science Institute
Basic Part Properties
- Part Display Name
- Interleukin 1 alpha
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2003-03-05
- Construct for LOINC Short Name
- Il1Alpha
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 白细胞介素 1 Alpha Synonyms: IL-1A; |
| fr-CA | French (Canada) | Interleukine 1 alpha |
| et-EE | Estonian (Estonia) | Interleukiin-1-alfa |
| es-ES | Spanish (Spain) | Interleucina 1 alfa |
| it-IT | Italian (Italy) | Interleuchina 1 alfa |
| tr-TR | Turkish (Turkey) | İnterlökin 1 alfa |
| ru-RU | Russian (Russian Federation) | Интерлейкин 1 альфа |
| nl-NL | Dutch (Netherlands) | interleukine 1 alfa |
| fr-BE | French (Belgium) | Interleukine 1 alpha Synonyms: IL 1alpha |
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