Version 2.77

Description

Anti-PCA-2 (purkinje cell cytoplasmic antibody type 2) autoantibodies are important markers of neurological autoimmunity related to cancer. PCA-2 binds to cerebellar Purkinje somata and dendrites, neurons in internal granular layer and dentate nucleus, and neuronal elements in gut and kidney. Patients present with mixed subacute neurological diorders, including brainstem or limbic encephalitis, cerebellar ataxia, Lambert-Eaton myasthenic syndrome, and autonomic and motor neuropathy. Patients with symptoms of such disorders, especially those with known risk factors for cancer, will undergo testing for paraneoplastic antibodies, including PCA-2. Testing is also performed to monitor the immune response of seropositive patients in the course of cancer therapy. PMID: 10716248 Source: Regenstrief LOINC

Basic Part Properties

Part Display Name
PCA-2
Part Type
Component (Describes the core component or analyte measured)
Created On
2003-04-22
Construct for LOINC Short Name
PCA-2

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP31708-8

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 浦肯雅细胞胞浆 2 型
Synonyms: 浦肯雅细胞胞浆（细胞浆、细胞质、胞质） 2 型;浦肯雅细胞 2 型;2 型 Purkinje 细胞;2 型朴金耶细胞;2 型浦肯雅细胞;2 型浦金埃细胞;Purkinje 细胞 2 型;朴金耶细胞 2 型;浦金埃细胞 2 型
fr-CA French (Canada) Cellules de Purkinje cytoplasmique type 2
es-ES Spanish (Spain) Células de Purkinje tipo 2
it-IT Italian (Italy) Cellule di Purkinje tipo 2
tr-TR Turkish (Turkey) Purkinje hücreleri tip 2
ru-RU Russian (Russian Federation) Пуркинье клетки тип 2
nl-NL Dutch (Netherlands) purkinjecellen type 2
fr-BE French (Belgium) Cellules de Purkinje type 2
pl-PL Polish (Poland) Cytoplazmatyczne typu 2 komórek Purkinjego
Synonyms: PCA-2