LP31861-5
SLC22A18 gene
Active
Description
The SLC22A18 gene (solute carrier family 22, member 18) [HGNC Gene ID:10964] is located on chromosome 11p15.5. This gene is one of several tumor-suppressing subtransferable fragments located in the imprinted gene domain of 11p15.5, an important tumor-suppressor gene region. Alterations in this region have been associated with the Beckwith-Wiedemann syndrome, Wilms tumor, rhabdomyosarcoma, adrenocortical carcinoma, and lung, ovarian, and breast cancer. This gene is imprinted, with preferential expression from the maternal allele. Mutations in this gene have been found in Wilms' tumor and lung cancer. This protein may act as a transporter of organic cations, and have a role in the transport of chloroquine and quinidine-related compounds in kidney. Two alternatively spliced transcript variants encoding the same protein have been described. [provided by RefSeq, Oct 2010] [NCBI Gene ID:5002] Source: National Center for Biotechnology Information (NCBI) Gene
Reference Information
| Type | Source | Reference |
|---|---|---|
| Webcontent | Online Mendelian Inheritance in Man®Copyright OMIM® and Online Mendelian Inheritance in Man® are registered trademarks of the Johns Hopkins University. | Link to OMIM |
Basic Part Properties
- Part Display Name
- SLC22A18 gene
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2003-08-08
- Construct for LOINC Short Name
- SLC22A18 gene
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | SLC22A18 基因 Synonyms: Beckwith-Wiedemann 综合征 染色体区域 1, 候选 a; |
| et-EE | Estonian (Estonia) | SLC22A18 geen |
| es-ES | Spanish (Spain) | Gen SLC22A18 |
| it-IT | Italian (Italy) | SLC22A18, gene Synonyms: Gene SLC22A18 |
| tr-TR | Turkish (Turkey) | SLC22A18 geni |
| ru-RU | Russian (Russian Federation) | SLC22A18 ген |
| nl-NL | Dutch (Netherlands) | SLC22A18-gen Synonyms: SLC22A18 gen |
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