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The major protein component of high density lipoproteins. It is instrumental in promoting efflux of cholesterol from extrahepatic tissue to the liver where it is metabolized and excreted from the body. The compound is the activator of lecithin-cholesterol acyltransferase which forms cholesteryl esters in HDL. The gene for this apolipoprotein is found on the long arm of chromosome 11. Source: National Library of Medicine, MeSH 2006

Apolipoproteins are a family of proteins involved in cholesterol transport and metabolism. Apoliprotein A is an important component of high-density lipoprotein (HDL or "good" cholesterol) and has several subtypes, including A-I and A-II, which are encoded by the APOA1 and APOA2 genes, respectively. A-I and A-II are the primary protein components of HDL. Deficiency of apolipoprotein A-I is associated with low HDL levels [], while deficiency of A-II is not associated with significant changes in HDL or other lipid levels [UniProt: P02652]. Source: Regenstrief LOINC, UniProt: P02652

Basic Part Properties

Part Display Name
Apolipoprotein A-I
Part Type
Divisors (Divisors only)
Created On
Construct for LOINC Short Name
Apo A-I

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Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 载脂蛋白 A-I
Synonyms: 载脂蛋白 AⅠ
fr-CA French (Canada) Apolipoprotéine A-I
et-EE Estonian (Estonia) apolipoproteiin A1
es-ES Spanish (Spain) Apolipoproteína A1
it-IT Italian (Italy) Apolipoproteina A-I
tr-TR Turkish (Turkey) Apolipoprotein A-I
ru-RU Russian (Russian Federation) Аполипопротеин A-I
nl-NL Dutch (Netherlands) apolipoproteïne A-1
fr-BE French (Belgium) Apolipoprotéine A-I
pl-PL Polish (Poland) apolipoproteina A I