LP31988-6
Apolipoprotein A-I
Active
Descriptions
The major protein component of high density lipoproteins. It is instrumental in promoting efflux of cholesterol from extrahepatic tissue to the liver where it is metabolized and excreted from the body. The compound is the activator of lecithin-cholesterol acyltransferase which forms cholesteryl esters in HDL. The gene for this apolipoprotein is found on the long arm of chromosome 11. Source: National Library of Medicine, MeSH 2006
Apolipoproteins are a family of proteins involved in cholesterol transport and metabolism. Apoliprotein A is an important component of high-density lipoprotein (HDL or "good" cholesterol) and has several subtypes, including A-I and A-II, which are encoded by the APOA1 and APOA2 genes, respectively. A-I and A-II are the primary protein components of HDL. Deficiency of apolipoprotein A-I is associated with low HDL levels [http://www.uniprot.org/uniprot/P02647], while deficiency of A-II is not associated with significant changes in HDL or other lipid levels [UniProt: P02652]. Source: Regenstrief LOINC, UniProt: P02652
Basic Part Properties
- Part Display Name
- Apolipoprotein A-I
- Part Type
- Divisors (Divisors only)
- Created On
- 2003-09-03
- Construct for LOINC Short Name
- Apo A-I
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 载脂蛋白 A-I Synonyms: 载脂蛋白 AⅠ |
| fr-CA | French (Canada) | Apolipoprotéine A-I |
| et-EE | Estonian (Estonia) | apolipoproteiin A1 |
| es-ES | Spanish (Spain) | Apolipoproteína A1 |
| it-IT | Italian (Italy) | Apolipoproteina A-I |
| tr-TR | Turkish (Turkey) | Apolipoprotein A-I |
| ru-RU | Russian (Russian Federation) | Аполипопротеин A-I |
| nl-NL | Dutch (Netherlands) | apolipoproteïne A-1 |
| fr-BE | French (Belgium) | Apolipoprotéine A-I |
| pl-PL | Polish (Poland) | apolipoproteina A I |
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