LP32149-4
Renin
Active
Descriptions
Molecular structure of renin Symbol(s):REN Other names: Angiotensinogenase Genetic data Locus:Chr. 1 q32 Protein StructureFunction Protein length: 406 (Amino Acids) Molecular Weight: 45060 (Da) Functions: Converts angiotensinogen to angiotensin I Motifs: SP motif Alternative Products: 2 known isoforms produced from alternative splicing Other Taxa expressing:Homo sapiens ; homologs many metazoan taxa Subcellular localization: Extracellular Biophysicochemical properties: K M =1 µmolL for angiotensinogen Database Links EC number:3.4.23.15 Codes: EntrezGene 5972 ; Mendelian Inheritance in Man [OMIM: 179820] ; RefSeq NM_000537 ; [UniProt: P00797] Renin, also known as angiotensinogenase, is a circulating enzyme released mainly by juxtaglomerular cells in the JGA of the kidneys in response to low blood volume or low body NaCl content, mediated through the rapid release of prostaglandins. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Renin (Wikipedia)
An enzyme which is secreted by the KIDNEY and is formed from prorenin in plasma and kidney. The enzyme cleaves the Leu-Leu bond in ANGIOTENSINOGEN to generate ANGIOTENSIN I. This enzyme was formerly listed as EC 3.4.99.19. Source: National Library of Medicine, MeSH 2006
Basic Part Properties
- Part Display Name
- Renin
- Part Type
- Divisors (Divisors only)
- Created On
- 2003-09-03
- Construct for LOINC Short Name
- Renin
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 肾素 Synonyms: 肾活素 |
| fr-CA | French (Canada) | Rénine |
| et-EE | Estonian (Estonia) | reniin |
| es-ES | Spanish (Spain) | Renina |
| it-IT | Italian (Italy) | Renina |
| tr-TR | Turkish (Turkey) | Renin |
| ru-RU | Russian (Russian Federation) | Ренин |
| nl-NL | Dutch (Netherlands) | renine |
| fr-BE | French (Belgium) | Rénine |
| pl-PL | Polish (Poland) | renina |
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