Version 2.80

Descriptions

MET gene amplification studies evaluate the number of copies of the MET gene present in a single cell. Amplification is determined based on the MET gene copy number and MET to centromere ratio. Different criteria have been proposed for what constitutes amplification, including a MET to centromere ratio of >= 2, an average MET gene copy number >=5, and at least 15 gene copies in 10% of the tumor cell nuclei that were counted. MET amplification is associated with worse prognosis in a variety of cancers, including non-small cell lung and gastroesophageal cancer. PMID: 27926778 Source: Regenstrief LOINC

The ratio of MET signals per nucleus to chromosome 7 signals per nucleus is used to determine if MET gene amplification has occurred. MET amplification is a biomarker for different types of cancer, including non-small cell lung cancer. Source: Regenstrief LOINC

Basic Part Properties

Part Name
MET gene copy number
Part Display Name
MET gene copy number
Part Type
Component (Describes the core component or analyte measured)
Created On
2019-05-03
Construct for LOINC Short Name
MET copy num

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP343942-1

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) MET 基因拷贝数
Synonyms: MET 基因拷贝（副本）数（数量、计数）
nl-NL Dutch (Netherlands) aantal kopieën van MET-gen
Synonyms: MET
it-IT Italian (Italy) MET, numero copia del gene
Synonyms: Numero copia del gene MET
es-ES Spanish (Spain) Número de copia del gen MET
el-GR Greek (Greece) Αριθμός αντιγράφων γονιδίου MET
Synonyms: Αριθμός αντιγράφων γονιδίου MET