LP344995-8
FGA gene & FGB gene & FGG gene
Active
Description
The FGA, FGB and FGG genes encode the 3 distinct protein subunits of fibrinogen, which has a well-established role in formation of the fibrin matrix of blood clots after proteolysis by factor IIa. Mutations resulting in fibrinogen disorders can be either quantitative (afibrinogenemia or hypofibrinogenemia) or functional (dysfibrinogenemia), and can affect any of the 3 subunits. Clinical severity can be highly variable, manifested as bleeding of the CNS GI, GU, skin, or umbilical cord neonatally. Not surprisingly, those with the lowest levels (below 0.5 g/L) are associated with more severe bleeding. Those with dysfibrinogenemia can have either bleeding or thromboembolic complications. PMID: 29844251 Source: Regenstrief LOINC
Basic Part Properties
- Part Name
- FGA gene & FGB gene & FGG gene
- Part Display Name
- FGA, FGB, and FGG gene
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2019-05-14
- Construct for LOINC Short Name
- FGA + FGB + FGG
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=LP344995-8
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | FGA 基因 & FGB 基因 & FGG 基因 |
| it-IT | Italian (Italy) | FGA, gene & FGB, gene & FGG, gene Synonyms: Geni FGA, FGB, e FGG |
| nl-NL | Dutch (Netherlands) | FGA-gen & FGB-gen & FGG-gen |
| es-ES | Spanish (Spain) | Genes FGA, FGB, y FGG |
| el-GR | Greek (Greece) | Γονίδιο FGA & γονίδιο FGB & γονίδιο FGG Synonyms: Γονίδιο FGA & γονίδιο FGB & γονίδιο FGG |
LOINC Copyright
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