Version 2.77

Descriptions

Anti-Müllerian hormone also known as AMH is a protein that, in humans, is encoded by the AMH gene. It inhibits the development of the Müllerian ducts (paramesonephric ducts) in the male embryo. It has also been called Müllerian inhibiting factor (MIF), Müllerian inhibiting hormone (MIH), and Müllerian inhibiting substance (MIS). It is named after Johannes Peter Müller.
In men, inadequate embryonal AMH activity can lead to the Persistent Müllerian duct syndrome (PMDS), in which a rudimentary uterus is present and testes are usually undescended. The AMH gene (AMH) or the gene (AMH-RII) for its receptor are usually abnormal. AMH measurements have also become widely used in the evaluation of testicular presence and function in infants with intersex conditions, ambiguous genitalia, and cryptorchidism. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

Mullerian inhibiting substance (MIS) is a gonadal hormone responsible for inducing the degeneration of the Mullerian ducts in male embryogenesis and assists in female egg maturation and release. This glycoprotein ensures that males do not develop a female reproductive tract during their early development and is crucial for females during childbirth. In males, MIS is stored in Sertoli cells in the testes and are released in order to differentiate cells and regulate reproductive tract growth. The MIS content in the blood may be measured in both females and infant boys. The MIS blood content is measured in male infants that have ambiguous genitalia or improperly formed testicles. The MIS blood content in females may be measured to predict menopause or time left to conceive. PMID: 8325249[Lab Tests Online:anti-mullerian-hormone/tab/test] Source: Regenstrief LOINC

Basic Part Properties

Part Display Name
Mullerian inhibiting substance
Part Type
Component (Describes the core component or analyte measured)
Created On
2004-10-20
Construct for LOINC Short Name
MIS

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CodeSystem lookup
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Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 苗勒氏管抑制物质
Synonyms: AMH;MIF;MIH;MIS;抗苗勒民管激素;抗苗勒激素;抗苗勒管激素;抗苗勒管激素（Anti Mullerian hormone，AMH）;抗苗氏管物质;米勒管抑制因子;米勒管抑制因子（Mullerian inhibiting factor，MIF）;苗勒抑制激素;苗勒抑制激素（Mullerian inhibiting hormone，MIH）;苗勒抑制物质;苗勒氏管抑制物质（Mullerian inhibiting substance，MIS）;苗勒管抑制物
fr-CA French (Canada) Substance antimüllerienne
es-ES Spanish (Spain) Sustancia inhibidora mulleriana
it-IT Italian (Italy) Sostanza inibitrice Mulleriana
tr-TR Turkish (Turkey) Mullerian inhbe edici substans
ru-RU Russian (Russian Federation) Мюллерова ингибирующая субстанция
Synonyms: Антимюллеров гормон;Мюллеров ингибирующий гормон
nl-NL Dutch (Netherlands) anti-Müllershormoon
Synonyms: Anti-Mulleriaans hormoon; Anti-|Mullerian hormoon
fr-BE French (Belgium) Substance antimüllerienne
Synonyms: Hormone antimullérienne