LP34979-2
Zinc finger protein of the cerebellum 4
Active
Description
Paraneoplastic neurological syndrome (PNS) is an autoimmune disorder that is manifested by progressive central, peripheral and/or autonomic nervous system symptoms. The neurological symptoms include encephalitis, autonomic failure, peripheral neuropathy, cerebellar ataxia, visual complaints and more. The antibodies that attack the neural tissue develop in response to tumor cells. The neoplasm may or may not be detectable using conventional imaging modalities. Since PNS can be associated with multiple antibodies testing usually includes a panel of PNS antibodies. In addition, the different PNS antibodies are associated with certain cancers so the antibody pattern can assist in identifying the specific tumor if it was previously undiagnosed. PMID: 22412264 Of patients positive for the zinc finger protein of the cerebellum 4 (Zic4) antibodies, ninety-two percent were diagnosed with small cell lung cancer. Zic4 antibodies often occur concurrently with Hu and CRMP5 antibodies. PMID: 15007130 Source: Regenstrief LOINC
Basic Part Properties
- Part Display Name
- Zinc finger protein of the cerebellum 4
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2005-01-03
- Construct for LOINC Short Name
- Zic4
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- CodeSystem lookup
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 小脑锌指蛋白 4 Synonyms: Zic4; |
| fr-CA | French (Canada) | Protéine à doigt de zinc du cervelet 4 |
| es-ES | Spanish (Spain) | Proteína dedo de zinc del cerebelo 4 |
| it-IT | Italian (Italy) | Zinc finger, proteina del cervelletto 4 Synonyms: Proteina zinc finger del cervelletto 4 |
| tr-TR | Turkish (Turkey) | Çinko parmak proteini, serebellum 4'ün |
| ru-RU | Russian (Russian Federation) | Цинк-пальцевый белок мозжечка 4 |
| nl-NL | Dutch (Netherlands) | zinc finger proteïne of the cerebellum 4 |
| fr-BE | French (Belgium) | Protéine-zinc en doigt du cervelet 4 |
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