LP36161-5
Salicylurate
Active
Description
Salicyluric acid is an aryl glycine conjugate formed by the body to eliminate excess salicylates, including aspirin. Aspirin is rapidly hydrolysed to salicylic acid which is further metabolized to various compounds, including salicyluric acid (SU) as well as various acyl and phenolic glucuronides, and hydroxylated metabolites. SU is the major metabolite of SA excreted in urine and it is present in the urine of people who have not taken salicylate drugs, although it has no anti-inflammatory effects in humans or in animals. More salicyluric acid (SU) is excreted in the urine of vegetarians than in non-vegetarians, primarily because fruits and vegetables are important sources of dietary salicylates. However, significantly less (10-15X) SU is excreted by vegetarians than individuals taking low-dose aspirin. PMID: 12944546 The induction of the salicyluric acid formation is one of the saturable pathways of salicylate elimination. The formation of the methyl ester of salicyluric acid is observed during the quantitation of salicyluric acid and other salicylate metabolites in urine by high-pressure liquid chromatography. This methyl ester formation causes artificially low values for salicyluric acid and high values for salicylic acid. PMID: 6101164 PMID: 6857178 Copyright Copyright ©2005-2009 Genome Alberta (Reference to original publication: Wishart DS, Knox C, Guo AC, et al. HMDB: a knowledgebase for the human metabolome. Nucleic Acids Res. 2009 37(Database issue):D603-610.) Source: Human Metabolome Database, Salicyluric acid
Basic Part Properties
- Part Display Name
- Salicylurate
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2005-10-07
- Construct for LOINC Short Name
- Salicylurate
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Language Variants Get Info
Tag | Language | Translation |
---|---|---|
zh-CN | Chinese (China) | 水杨尿酸 Synonyms: 2-羟基苯甲酰甘氨酸; |
fr-CA | French (Canada) | Salicylurate |
et-EE | Estonian (Estonia) | Salitsüüluraat |
es-ES | Spanish (Spain) | Salicilurato |
it-IT | Italian (Italy) | Salicilurato |
tr-TR | Turkish (Turkey) | Salisilürat |
ru-RU | Russian (Russian Federation) | Салицилурат |
nl-NL | Dutch (Netherlands) | salicyluraat |
fr-BE | French (Belgium) | Salicylurate |
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