Version 2.77

Descriptions

Ganglioside antibodies are associated with diverse peripheral neuropathies. Elevated antibody levels to ganglioside-monosialic acid (GM1) are associated with motor or sensorimotor neuropathies, particularly multifocal motor neuropathy. Anti-GM1 may occur as IgM (polyclonal or monoclonal) or IgG antibodies. These antibodies may also be found in patients with diverse connective tissue diseases as well as normal individuals. Source: ARUP Laboratories, GM1

Levels of anti-GM1 are elevated in patients with various forms of dementia. Antibodies levels correlate with more severe Guillain-Barré syndrome. In Japan, levels to GM1 were elevated in patients with prodromal diarrhea. Titers to GM1 in other diseases (rheumatoid arthritis, primary Sjögren's syndrome and systemic lupus erythematosus) was also elevated. Highly significant association was found with rheumatoid arthritis and peripheral neuropathies. Conflicting evidence suggests no significant elevation in motor neuron neuropathy but marginally elevated IgA in sensory neuron neuropathies. The autoimmune role of anti-GM1 is still unclear. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Wikipedia

Basic Part Properties

Part Display Name
Ganglioside GM1 Ab
Part Type
Component (Describes the core component or analyte measured)
Created On
2006-05-09

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Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 神经节苷脂 GM1 抗体
Synonyms: 神经节苷脂 GM1 Ab
pl-PL Polish (Poland) Gangliozyd GM1 Ab
Synonyms: Przeciwciała do gangliozydu GM1