Version 2.77


Purkinje cell cytoplasmic-Tr (PCA-Tr) antibodies are associated with Hodgkin's lymphoma. The clinical presentation that corresponds with PCA-Tr antibodies includes paraneoplastic cerebellar degeneration (PCD) and limbic encephalopathy (LE). PMID: 22412264 PCD and LE are types of paraneoplastic neurological syndrome (PNS), an autoimmune disorder that is manifested by progressive neurological syndromes of any combination of the central, peripheral and autonomic nervous systems. The antibodies that attack the neural tissue develop in response to tumor cells. The neurological symptoms include encephalitis, autonomic failure, peripheral neuropathy, cerebellar ataxia, visual complaints and more. The neoplasm may or may not be detectable using conventional imaging modalities. Since PNS can be associated with multiple antibodies, testing usually includes a panel of PNS antibodies. In addition, the different PNS antibodies are associated with certain cancers so the antibody pattern can assist in identifying the specific tumor if it was previously undiagnosed. PMID: 22412264 Source: Regenstrief LOINC

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Tag Language Translation
zh-CN Chinese (China) 浦肯雅细胞 TR 型抗体
Synonyms: Purkinje 细胞 Tr 型 Ab;Purkinje 细胞 Tr 型抗体;Tr 型 Purkinje 细胞 Ab;Tr 型 Purkinje 细胞抗体;TR 型朴金耶细胞 Ab;TR 型朴金耶细胞抗体;TR 型浦肯雅细胞 Ab;TR 型浦肯雅细胞抗体;TR 型浦金埃细胞 Ab;TR 型浦金埃细胞抗体;朴金耶细胞 Tr 型 Ab;朴金耶细胞 Tr 型抗体;浦肯雅细胞 Tr 型 Ab;浦肯雅细胞 Tr 型抗体;浦金埃细胞 Tr 型 Ab;浦金埃细胞 Tr 型抗体
pl-PL Polish (Poland) Komórki Purkiniego typ Tr cytoplazmatyczne Ab
Synonyms: Przeciwciała typu Tr do cytoplazmy komórki Purkinjego