LP410867-8
Thrombospondin type I domain-containing 7A
Active
Description
Thrombospondin type-1 domain-containing protein 7A (THSD7A) is a membrane protein that was initially characterized in placental endothelia, but is also expressed on the basal aspect of podocytes of the kidney. It has been reported to play a role in actin cytoskeletal integrity, and its soluble form has been shown to promote endothelial cell migration and filopodia formation. Autoantibodies against THSD7A have been demonstrated to be present in a small subset of patients with idiopathic/primary membranous nephropathy (MN) who do not demonstrate antibodies against the primary target in that disease, the phospholipase A2 receptor (PLA2R) PMID: 25394321. Source: Regenstrief LOINC
Basic Part Properties
- Part Name
- Thrombospondin type I domain-containing 7A
- Part Display Name
- Thrombospondin type I domain-containing 7A
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2019-07-03
- Construct for LOINC Short Name
- THSD7A
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | I 型血小板反应蛋白 7A 域 Synonyms: 血小板反应结构域蛋白7A; |
| it-IT | Italian (Italy) | Trombospondina di tipo 1 Synonyms: THBS1 |
| fr-FR | French (France) | THSD7A |
| es-ES | Spanish (Spain) | Trombospondina de tipo I 7A que contiene el dominio |
| pl-PL | Polish (Poland) | Trombospondyna typu I z domeną 7A Synonyms: THSD7A |
| el-GR | Greek (Greece) | Τομέας που περιέχει θρομβοσπονδίνη τύπου Ι 7Α Synonyms: Τομέας που περιέχει θρομβοσπονδίνη τύπου Ι 7Α |
LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://