LP411611-9
Large B-cell lymphoma
Active
Description
Distinguishing between large B-cell lymphomas is critical because the different forms often require distinct management. Diffuse large B-cell lymphoma (DLBCL) is the most common form, making up 30-40% of all non-Hodgkin's lymphomas. DLBCL is defined pathologically by large neoplastic cells with B-cell derivation and clinically by aggressive presentation, but differs from its former putative subtype, primary mediastinal large B-cell lymphoma (PMBCL), which is believed to arise from thymic medullary B cells. Since 2001, the WHO has recognized PMBCL as a distinct clinicopathologic disease from DLBCL, with likely distinct treatment options. PMBCL accounts for approximately 2% of patients with NHL, and tends to affect younger patients. PMID: 16720849. PMBCL is generally not further subclassified during a patient workup, whereas DLBCL can be further subdivided by cell of origin (COO) into germinal center type and non-germinal center (activated B-cell) type, the latter having significantly worse response to certain treatments PMID: 25135992. Source: Regenstrief LOINC
Basic Part Properties
- Part Display Name
- Large B-cell lymphoma
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2019-09-17
- Construct for LOINC Short Name
- Lg B-cell lymph
LOINC Terminology Service (API) using HL7® FHIR® Get Info
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- CodeSystem lookup
- https:
//fhir.loinc.org/CodeSystem/$lookup?system=http: //loinc.org&code=LP411611-9
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 大B细胞淋巴瘤 Synonyms: LBCL |
| it-IT | Italian (Italy) | Linfoma a grandi cellule B |
| es-ES | Spanish (Spain) | Linfoma de células B grandes |
| pl-PL | Polish (Poland) | Chłoniak z dużych komórek typu B |
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