Version 2.77

Description

Distinguishing between large B-cell lymphomas is critical because the different forms often require distinct management. Diffuse large B-cell lymphoma (DLBCL) is the most common form, making up 30-40% of all non-Hodgkin's lymphomas. DLBCL is defined pathologically by large neoplastic cells with B-cell derivation and clinically by aggressive presentation, but differs from its former putative subtype, primary mediastinal large B-cell lymphoma (PMBCL), which is believed to arise from thymic medullary B cells. Since 2001, the WHO has recognized PMBCL as a distinct clinicopathologic disease from DLBCL, with likely distinct treatment options. PMBCL accounts for approximately 2% of patients with NHL, and tends to affect younger patients. PMID: 16720849. PMBCL is generally not further subclassified during a patient workup, whereas DLBCL can be further subdivided by cell of origin (COO) into germinal center type and non-germinal center (activated B-cell) type, the latter having significantly worse response to certain treatments PMID: 25135992. Source: Regenstrief LOINC

Basic Part Properties

Part Display Name
Large B-cell lymphoma classification panel
Part Type
Component (Describes the core component or analyte measured)
Created On
2019-09-17
Construct for LOINC Short Name
Lg B-cell Lymph Pnl

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP411616-8

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 大B细胞淋巴瘤分类组套
Synonyms: 大B细胞淋巴瘤（LBCL）分类组套（组合、医嘱组、套餐、套餐医嘱、医嘱套餐、组合申请、组合项目）
it-IT Italian (Italy) Linfoma a grandi cellule B, panel classificazione
Synonyms: Panel classificazione di linfoma a grandi cellule B
es-ES Spanish (Spain) Panel de clasificación de linfomas de células B grandes
pl-PL Polish (Poland) Klasyfikacja chłoniaka z dużych komórek B, panel
Synonyms: Klasyfikacja chłoniaka z dużych komórek B, panel