Version 2.80

Description

The 5-HTTLPR variant in the SLC6A4 (solute carrier family 6 (neurotransmitter transporter), member 4) gene is a 44-base pair promoter insertion/deletion polymorphism that has been shown to affect the rate of serotonin uptake in patients. It may also play a role in sudden infant death syndrome, aggressive behavior in Alzheimer disease patients, and depression-susceptibility in people experiencing emotional trauma.[NCBI Gene ID:6532] The serotonin transporter polymorphism results in either a long allele (L) or short allele (S) of the gene. The "L" allele is associated with normal levels of serotonin transporter, and the "S" allele is associated with reduced serotonin transporter levels and increased risk for depression. PMID: 17063469 Source: Regenstrief LOINC

Basic Part Properties

Part Name
SLC6A4 gene 5-HTTLPR variant
Part Display Name
SLC6A4 gene 5-HTTLPR variant
Part Type
Component (Describes the core component or analyte measured)
Created On
2020-01-29
Construct for LOINC Short Name
SLC6A4 5-HTTLPR

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP417576-8

Language Variants Get Info

Tag Language Translation
nl-NL Dutch (Netherlands) SLC6A4-gen 5-HTTLPR variant
zh-CN Chinese (China) SLC6A4 基因 5-HTTLPR 变异
Synonyms: SLC6A4 基因 5-HTTLPR 变异（变型、变异体）
it-IT Italian (Italy) SLC6A4, gene 5-HTTLPR, variante
es-ES Spanish (Spain) Variante 5-HTTLPR del gen SLC6A4
el-GR Greek (Greece) Γονίδιο SLC6A4 παραλλαγή 5-HTTLPR
Synonyms: Γονίδιο SLC6A4 παραλλαγή 5-HTTLPR