Version 2.80

Description

Translocations of the immunoglobulin heavy chain (IgH) gene at 14q32 are routinely present in patients with B lymphoid malignancies and is one of the most common mutations in patients with multiple myeloma (MM). The t(14;20)(q32;q12) translocation may cause the deregulation of existing oncogenes or produce new hybrid genes with altered characteristics. The t(14;20) translocation is detected in very early stages of disease, indicating it may play a role in instigating its development. IgH translocations increase as the disease progresses. The t(14q32) translocation is present in 74% of patients with MM and in 85% of patients with plasma cell leukemia. PMID: 15257707 Source: Regenstrief LOINC

Basic Part Properties

Part Name
Chromosome region 14q32 rearrangements
Part Display Name
Chromosome region 14q32 rearrangements
Part Type
Component (Describes the core component or analyte measured)
Created On
2020-04-22
Construct for LOINC Short Name
Chr 14q32 Rearr

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP418221-0

Language Variants Get Info

Tag Language Translation
zh-CN Chinese (China) 染色体区域 14q32 重排
Synonyms: 染色体区域（染色体部位、染色体区、染色体区带、染色体部） 14q32 重排
nl-NL Dutch (Netherlands) chromosomale recombinatie van regio 14q32
it-IT Italian (Italy) Regione cromosomica14q32, riarrangiamenti
es-ES Spanish (Spain) Reordenamientos de la región cromosómica 14q32
pl-PL Polish (Poland) Rearanżacje w regionie chromosomowym 14q32
el-GR Greek (Greece) Αναδιατάξεις χρωμοσωμικής περιοχής 14q32
Synonyms: Αναδιατάξεις χρωμοσωμικής περιοχής 14q32