LP420965-8
Cyclin-dependent kinase 4
Active
Description
Cyclin-dependent kinase 4 (CDK4) is encoded by the CDK4 gene and plays a role in regulating the cell cycle during the transition between G1 and S phases. Mutations in the CDK4 gene are associated with cutaneous malignant melanoma 3. [UniProt: P11802] CDK4 inhibitors, including palbociclib, ribociclib, and abemaciclib, are used to treat patients with HR+/HER2− advanced breast cancer. PMID: 29847850 Source: Regenstrief LOINC
Basic Part Properties
- Part Name
- Cyclin-dependent kinase 4
- Part Display Name
- Cyclin-dependent kinase 4
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2020-11-05
- Construct for LOINC Short Name
- CDK4
LOINC Terminology Service (API) using HL7® FHIR® Get Info
Requests to this service require a free LOINC username and password. Below is a sample of the possible capabilities. See the LOINC Terminology Service documentation for more information.
Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| it-IT | Italian (Italy) | Chinasi 4 ciclina-dipendente |
| es-ES | Spanish (Spain) | Quinasa 4 dependiente de ciclina |
| zh-CN | Chinese (China) | 细胞周期蛋白依赖性激酶 4 Synonyms: 细胞分裂蛋白激酶 4; |
| nl-NL | Dutch (Netherlands) | cycline-afhankelijk kinase 4 |
| pl-PL | Polish (Poland) | Kinaza cyklinozależna 4 |
| el-GR | Greek (Greece) | Κυκλινοεξαρτώμενη κινάση 4 Synonyms: Κυκλινοεξαρτώμενη κινάση 4 |
LOINC Copyright
Copyright © Regenstrief Institute, Inc. All Rights Reserved. To the extent included herein, the LOINC table and LOINC codes are copyright © Regenstrief Institute, Inc. and the Logical Observation Identifiers Names and Codes (LOINC) Committee. See https://