Version 2.76

Description

Yersinia outer proteins (Yops) are plasmid-encoded proteins that help counteract the host immune response. The low-calcium response protein (LcrV) is not technically an outer protein but is associated with Yops. All of the Yops use a protein export pathway called TTSS, which enables injection of the virulence proteins into host cells. Inside the host cells, different Yops have different targets and functions.
1. YopN, YopB, YopD, and LcrV interact with the TTSS to enable host cell entry
2. YopE, YopO, YopH, and YopT interfere with host GTPase activity
3. YopM interferes with host caspase-1 activity
4. YopP inhibits NF-kB activation
PMID: 27281989 Source: Regenstrief LOINC

Basic Part Properties

Part Display Name
Yersinia outer protein P
Part Type
Component (Describes the core component or analyte measured)
Created On
2021-04-02
Construct for LOINC Short Name
YopP

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP426331-7

Language Variants Get Info

Tag Language Translation
it-IT Italian (Italy) Yersinia, proteina P della membrana esterna
Synonyms: Proteina P della membrana esterna di yersinia
es-ES Spanish (Spain) Proteína externa P de Yersinia
zh-CN Chinese (China) 耶尔森氏菌外膜蛋白 P
Synonyms: 耶尔森菌外膜蛋白 P;YopP