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Description

Ubiquitin carboxyl-terminal hydrolase-L1 (UCH-L1) is a protein that is involved in the metabolism of ubiquitin within neurons PMID: 10848595. Increases in blood UCH-L1 have been detected in the serum of mild and moderate TBI patients within an hour of injury PMID: 22673263. Levels measured within 4 hours of injury were significantly higher in those with TBI lesions on CT than those with a normal intracranial appearance on CT. Blood levels of UCH-L1 have been demonstrated to be able to discriminate mild TBI patients from patients without head injuries and, similar to GFAP, UCH-L1 levels were much higher in patients who required neurosurgical intervention PMID: 22673263. Source: Abbott Laboratories

Basic Part Properties

Part Name
Ubiquitin carboxyl-terminal hydrolase-L1
Part Display Name
Ubiquitin carboxyl-terminal hydrolase-L1
Part Type
Component (Describes the core component or analyte measured)
Created On
2021-04-22
Construct for LOINC Short Name
UCH-L1

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP426538-7

Language Variants Get Info

TagLanguageTranslation
fr-FRFrench (France)Ubiquitin carboxyl-terminal hydrolase-L1
it-ITItalian (Italy)Idrolasi dell'ubiquitina carbossi-terminale L1,Idrolasi dell''ubiquitina carbossi-terminale,Idrolasi dell''ubiquitina C-terminale,UCH-L1
es-ESSpanish (Spain)Ubiquitina carboxil-terminal hidrolasa-L1
zh-CNChinese (China)泛素羧基末端水解酶-L1
Synonyms: 泛素羧基末端水解酶-L1（泛素羧基末端水解酶 L1、UCHL1、UCHL1）
el-GRGreek (Greece)Υδρολάση του καρβοξυτελικού άκρου της ουβικιτίνης L1
Synonyms: Υδρολάση του καρβοξυτελικού άκρου της ουβικιτίνης L1