LP62881-5
Thyrotropin releasing hormone
Active
Description
Thyrotropin Releasing Hormone (TRH) is a tripeptide produced primarily by the hypothalamus. TRH is produced from a prohormone which contains multiple copies of the TRH molecule meaning that several TRH entities can be released from one precursor. It has a stimulatory effect on the pituitary releasing Thyrotropin (TSH). TRH secretion is controlled in a negative feedback system by thyroid hormones. Binding of TRH to its receptor causes a rise in calcium which initiates TSH secretion. It also stimulates adenyl cyclase in the pituitary. TRH also stimulates secretion of Prolactin, Growth Hormone in Acromegaly, and ACTH in Cushing's and Nelson's Syndromes. Levels of TRH are non-detectable or very low in patients with Hyperthyroidism and Hypothalamic Hypothyroidism. Levels are elevated in patients with Primary and Pituitary Hypothyroidism Source: Inter Science Institute, Inter Science Institute
Basic Part Properties
- Part Display Name
- Thyrotropin releasing hormone
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2007-03-21
- Construct for LOINC Short Name
- Thyrotropin releasing horm
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 促甲状腺激素释放激素 Synonyms: 促甲状腺素释放激素; |
| fr-CA | French (Canada) | TRH |
| et-EE | Estonian (Estonia) | Türeotropiini vabastav hormoon |
| es-ES | Spanish (Spain) | Hormona liberadora de tirotropina |
| it-IT | Italian (Italy) | Tireotropina, ormone di rilascio Synonyms: Ormone di rilascio del TSH |
| tr-TR | Turkish (Turkey) | Tirotropin salıcı hormon |
| ru-RU | Russian (Russian Federation) | Тиреотропин-рилизинг-гормон Synonyms: Тиреолиберин |
| nl-NL | Dutch (Netherlands) | TSH-releasing hormoon |
| fr-BE | French (Belgium) | TRH |
| pl-PL | Polish (Poland) | Tyreoliberyna |
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