LP6402-4
MLC
Active
Description
The minimum lethal concentration (MLC) is the most common procedure used to determine the minimum bactericidal concentration (MBC) or the minimum fungicidal concentration (MFC). A precise aliquot of culture from the MIC wells or tubes that exhibited no growth are sub-cultured onto a non-selective agar plate and allowed to incubate for 24 hours. The number of colony-forming units per milliliter (CFU/mL) is determined. The MBC is defined as the lowest concentration of antibiotic that kills 99.9% of the final inoculum after a 24 hour incubation an in accordance with the standardized conditions stated in document M26-A. The MFC is defined as the lowest concentration of drug that kills 98-99.9% when compared to the initial inoculum (the sample in the clear wells or tubes).[Balouiri, Mounyr., Sadiki, Moulay., Ibnsouda, Saad Koraichi. "Methods for in vitro evaluating antimicrobial activity: A review". Journal of Pharmaceutical Analysis. Volume 6 (2016): Pages 71-79.] Source: Regenstrief LOINC
Basic Part Properties
- Part Name
- MLC
- Part Display Name
- Minimum lethal concentration (MLC)
- Part Type
- Method (Describes the method by which the test was performed)
- Created On
- 2000-05-03
- Construct for LOINC Short Name
- MLC
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- CodeSystem lookup
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | 最小致死浓度法 Synonyms: 最低杀菌浓度; |
| es-ES | Spanish (Spain) | Concentración mínima bactericida (CMB) |
| it-IT | Italian (Italy) | MLC Synonyms: Concentrazione minima letale (MLC) |
| et-EE | Estonian (Estonia) | MLK Synonyms: Minimaalne letaalne kontsentratsioon |
| tr-TR | Turkish (Turkey) | MLC |
| fr-BE | French (Belgium) | CLM |
| fr-CA | French (Canada) | CLM |
| nl-NL | Dutch (Netherlands) | minimaal dodelijke concentratie Synonyms: MLC |
| pl-PL | Polish (Poland) | minimalne stężenie śmiertelne, MLC |
| el-GR | Greek (Greece) | MLC Synonyms: MLC |
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