LP65317-7
2-Dechloroethylifosfamide
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Description
2-Dechlroethylifosfamide (2-DCE-IF) is a metabolite that results from dealkylation of ifosfamide (IF), a chemotherapeutic agent used to treat solid tumors. The production of the 2-DCE-IF metabolites leads to equimolar amounts of chloroacetaldehyde, which is thought to be responsible for the nephrotoxic and neurotoxic adverse-effects associated with IF. Therefore, elevated levels of 2-DCE-IF lead to an increase risk for nephrotoxicity. PMID: 18825700 Source: Regenstrief LOINC, PMID: 18825700
Basic Part Properties
- Part Display Name
- 2-Dechloroethylifosfamide
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2007-09-12
- Construct for LOINC Short Name
- 2-DCE-IF
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Language Variants Get Info
Tag | Language | Translation |
---|---|---|
zh-CN | Chinese (China) | 2-脱氯乙基异环磷酰胺 Synonyms: 2d-Ifo; |
fr-CA | French (Canada) | 2-dechloroéthylifosfamide |
et-EE | Estonian (Estonia) | 2-dekloroetüülifosfamiid |
es-ES | Spanish (Spain) | 2-Decloroetilifosfamida |
it-IT | Italian (Italy) | 2-Decloroetilifosfamide |
tr-TR | Turkish (Turkey) | 2-Dekloroetilifosfamide |
ru-RU | Russian (Russian Federation) | 2-Дехлорэтилифосфамид |
nl-NL | Dutch (Netherlands) | 2-dechloorethylifosfamide |
fr-BE | French (Belgium) | 2-Dechloroéthylifosfamide |
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