Log In

Description

2-Dechlroethylifosfamide (2-DCE-IF) is a metabolite that results from dealkylation of ifosfamide (IF), a chemotherapeutic agent used to treat solid tumors. The production of the 2-DCE-IF metabolites leads to equimolar amounts of chloroacetaldehyde, which is thought to be responsible for the nephrotoxic and neurotoxic adverse-effects associated with IF. Therefore, elevated levels of 2-DCE-IF lead to an increase risk for nephrotoxicity. PMID: 18825700 Source: Regenstrief LOINC, PMID: 18825700

Basic Part Properties

Part Name
2-Dechloroethylifosfamide
Part Display Name
2-Dechloroethylifosfamide
Part Type
Component (Describes the core component or analyte measured)
Created On
2007-09-12
Construct for LOINC Short Name
2-DCE-IF

LOINC Terminology Service (API) using HL7® FHIR® Get Info

CodeSystem lookup
https://fhir.loinc.org/CodeSystem/$lookup?system=http://loinc.org&code=LP65317-7
ConceptMap translate
https://fhir.loinc.org/ConceptMap/$translate?system=http://loinc.org&code=LP65317-7

Language Variants Get Info

TagLanguageTranslation
zh-CNChinese (China)2-脱氯乙基异环磷酰胺
Synonyms: 2d-Ifo;2D-ifosfamide;2D-异环磷酰胺;2-脱氯乙基-异环磷酰胺;异环磷酰胺代谢产物
fr-CAFrench (Canada)2-dechloroéthylifosfamide
et-EEEstonian (Estonia)2-dekloroetüülifosfamiid
es-ESSpanish (Spain)2-Decloroetilifosfamida
it-ITItalian (Italy)2-Decloroetilifosfamide
tr-TRTurkish (Turkey)2-Dekloroetilifosfamide
ru-RURussian (Russian Federation)2-Дехлорэтилифосфамид
nl-NLDutch (Netherlands)2-dechloorethylifosfamide
fr-BEFrench (Belgium)2-Dechloroéthylifosfamide
fr-FRFrench (France)2-déchloroéthylifosfamide
el-GRGreek (Greece)2-Δεχλωροαιθυλιφοσφαμίδη
Synonyms: 2-Δεχλωροαιθυλιφοσφαμίδη
pl-PLPolish (Poland)2-Dechloroetylofosfamid