LP65897-8
BRCA1+BRCA2 gene
Active
Description
The BRCA1 gene (breast cancer 1, early onset) [HGNC Gene ID:1100] is located on chromosome 17 at position q21, and the BRCA2 gene (breast cancer 2, early onset) [HGNC Gene ID:1101] is located on chromosome 13 at position q12.3. Inherited mutations in BRCA1 and BRCA2 confer increased lifetime risk of developing breast or ovarian cancer. Mutations in the BRCA1 gene are responsible for approximately 40% of inherited breast cancers and more than 80% of inherited breast and ovarian cancers. Both BRCA1 and BRCA2 are involved in maintenance of genome stability, specifically the homologous recombination pathway for double-strand DNA repair.[NCBI Gene ID:672][NCBI Gene ID:675] Source: National Center for Biotechnology Information (NCBI) Gene
Basic Part Properties
- Part Display Name
- BRCA1+BRCA2 gene
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2007-11-02
- Construct for LOINC Short Name
- BRCA1+BRCA2
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- CodeSystem lookup
- https:
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| zh-CN | Chinese (China) | BRCA1+BRCA2 基因 |
| fr-CA | French (Canada) | Gène BRCA1+BRCA2 |
| et-EE | Estonian (Estonia) | BRCA1 + BRCA2 geen |
| es-ES | Spanish (Spain) | Genes BRCA1+BRCA2 |
| it-IT | Italian (Italy) | BRCA1+BRCA2, gene Synonyms: Gene BRCA1+BRCA2 |
| tr-TR | Turkish (Turkey) | BRCA1+BRCA2 geni |
| ru-RU | Russian (Russian Federation) | BRCA1+BRCA2 ген |
| nl-NL | Dutch (Netherlands) | BRCA1 + BRCA2-gen Synonyms: BRCA1+BRCA2 gen |
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