LP68274-7
Prolactin.monomeric
Active
Description
Monomeric prolactin is the most common form of circulating prolactin. Prolactin also has several isoforms, including the dimeric form ("big-prolactin") that has a molecular weight of ~50 kD and polymeric form ("big-big prolactin") that has a molecular weight of ~ 150 kD). Big-big prolactin, known as macroprolactin, and big prolactin are formed in the circulation after secretion of prolactin from the pituitary. They have a longer half-life than monomeric prolactin are not biologically active. However, typical prolactin assays do not differentiate between the different forms of prolactin, and the presence of big and big-big prolactin can lead to a false diagnosis of hyperprolactinemia. Methods such as PEG precipitation can separate macroprolactin and big prolactin from monomeric prolactin in order to obtain a more accurate measurement of biologically active prolactin, and chromatography can be used to further characterize the isoforms if necessary. PMCID: PMC3719302 Source: Regenstrief LOINC,
Basic Part Properties
- Part Display Name
- Prolactin monomeric
- Part Type
- Component (Describes the core component or analyte measured)
- Created On
- 2008-03-26
- Construct for LOINC Short Name
- Prolactin.monomeric
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Language Variants Get Info
| Tag | Language | Translation |
|---|---|---|
| et-EE | Estonian (Estonia) | Prolaktiin.monomeerne |
| es-ES | Spanish (Spain) | Prolactina monomérica |
| it-IT | Italian (Italy) | Prolattina.monomerica Synonyms: Prolattina monomerica |
| tr-TR | Turkish (Turkey) | Prolaktin.monomerik |
| ru-RU | Russian (Russian Federation) | Пролактин.мономер |
| nl-NL | Dutch (Netherlands) | prolactine.monomeer |
| fr-BE | French (Belgium) | Prolactine.monomérique Synonyms: PRL. Monomérique |
| zh-CN | Chinese (China) | 催乳素.单体 Synonyms: 催乳素（PRL、 |
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