LP68315-8

Megaloblasts

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Description

A megaloblast is an unusually large erythroblast that can be associated with pernicious anemia (Vitamin B12 deficiency) and folic acid deficiency (collectively called megaloblastic anemia). It is differentiated from a normoblast, which is a normally-sized erythroblast. This kind of anemia leads to macrocytes (abnormally large red cells). The cause of this cellular gigantism is an impairment in DNA synthesis which delays nuclear maturation and cell division. Because RNA and cytoplasmic elements are synthesized at a constant rate despite the cells impaired DNA synthesis the cells show nuclear-cytoplasmic asynchrony. Copyright Text is available under the Creative Commons Attribution/Share-Alike License. See http://creativecommons.org/licenses/by-sa/3.0/ for details. Source: Wikipedia, Megaloblast

Basic Part Properties

Part Name

Megaloblasts

Part Display Name

Megaloblasts

Part Type

Component (Describes the core component or analyte measured)

Created On

2008-03-28

Construct for LOINC Short Name

Megaloblasts

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